The transformation of multifunctional bio-patch to hydrogel on skin wounds for efficient scarless wound healing

The transformation of multifunctional bio-patch to hydrogel on skin wounds for efficient scarless wound healing

Blog Article

Hydrogels have been widely used in various biomedical 5-HTP applications, including skin regeneration and tissue repair.However, the capability of certain hydrogels to absorb exudate or blood from surrounding wounds, coupled with the challenge in their long-term storage to prevent bacterial growth, can pose limitations to their efficacy in biological applications.To address these challenges, the development of a multifunctional aloin-arginine-alginate (short for 3A) bio-patch capable of transforming into a hydrogel upon absorbing exudate or blood from neighboring wounds for cutaneous regeneration is proposed.The 3A bio-patch exhibits outstanding features, including an excellent porous structure, swelling properties, and biodegradability.

These characteristics allow for the rapid absorption of wound exudates CASUAL ACT and subsequent transformation into a hydrogel that is suitable for treating skin wounds.Furthermore, the 3A bio-patch exhibits remarkable antibacterial and anti-inflammatory properties, leading to accelerated wound healing and scarless repair in vivo.This study presents a novel approach to the development of cutaneous wound dressing materials.